This virtual Q&A session reviewed recent advancements in colorectal cancer (CRC) screening and discussed their implications for improving screening uptake and quality outcomes in health centers. Participants explored emerging evidence on screening modalities, follow-up strategies, and population-based approaches that address disparities in colorectal cancer outcomes. The session was structured around five pre-cleared question domains covering colonoscopy vs. stool-based testing, blood-based screening tests, follow-up colonoscopy rates, population-based screening equity, and the single most impactful action for improving CRC screening.